New mouse models of cataract for which chromosomal locations have been established

Gene(or Strain) Phenotype Description Chromosome
Lop10 Homozygous mice are microophthalmic with dense white cataracts; heterozygous mice have consistent variable expressivity dependent on background, AD     3
lop11 Recessive, vacuolated cataract, AR     8
Lop12 Dominant, nuclear lumpy irregular cataract Heterogygotes have intermediate sized eyes, AD     1
nm1853 Dominant cataract, Crygc mutation, AD     1
lop13 Early white cataract (former name nuc), AR     15
lop14 Extruded lens, found in Inversion line In38Rk, AR     14
lop16 Mutants die at 1 mo. have muscle paresis and cataract, AR     10
lop18 Cataract mapped to alpha-crystalline region, AR     17
corn1 Corneal epithelial dystrophy and white cataract by 42 days, AR     2
bs2 Blind-sterile-2, microophthalmia, cataracts, ptyergia, AR     2
Nm2249 Fetal cataract with microophthalmia, AD     3
lop20 Cataract, variable expression, AR     1
Lop21 Transgenic cataract, AD     16
nm1640 Cataract, homozygous males are sterile, AR     2
NM2620 Cataract (allelic to Cat), AD     10
nm3347 Cataract starts at 1 month of age, AR     5
NM2520 Cataract and coloboma in SJL at 3 months of age, AD     5
nm2897 Recessive cataract, AR     2
nm3364 Recessive cataract, AR     2
NM3062 Dominant cataract, AD     1

AD=autosomal dominant, AR=autosomal recessive, XD=X-linked Dominant, XR=X-linked recessive