Retinal degeneration 9 (Rd9)
Rd9 is an X-linked semidominant retinal degeneration model. In Rd9 mutants, the retina is covered with diffuse white spots (mottled). The fundus appears normal at weaning age and the retina becomes mottled starting at 6 weeks of age in heterozygous females. The fundus of homozygous females and hemizygous males have a blond appearance. Retinal pigment loss and electroretinogram response decreases with age.
|
Gene |
Mouse Chromosome |
Human Chromosome |
Retinal ONL disappear by |
Strains |
| Rd9 | X | Xp21.1 | 30 | C57BL/6J-Rd9 |
