GRC Strain submittal form

Donate a Strain to The Jackson Laboratory Repository

The Genetic Resources Committee meets once a month to make recommendations concerning the importation of submitted strains. To ensure that your strain is evaluated at the next meeting, please submit your strain no later than the 3rd Wednesday of the month. The information submitted on this form is used to evaluate your strain, so please include as much detail as possible. Please enter information for no more than one strain at a time. You will receive a confirmation email upon our receipt of your completed strain submission.  If you do not receive a confirmation email, or if you have any questions, please contact Deborah Boswell.

We strongly recommend that submitters read Information for Donating Investigators (.pdf). This document describes the responsibilities The Jackson Laboratory has in maintaining and distributing your strain as well as those responsibilities assumed by Donating Investigators.

Information is now available for scientists interested in participating in a Sponsored Strain Distribution program, whereby donors subsidize the costs associated with importation and cryopreservation. The Sponsored Strain Distribution program utilizes an expedited review process.

Contact Information

Your name:  REQUIRED
Institution:  REQUIRED
Street:
City: St: Zip:
Country:
Email:  REQUIRED
Phone:  REQUIRED
Fax:

Contact information for Principal Investigator
(Only if different from above contact information)

PI Name:
Institution:
Street:
City: St: Zip:
Country:
Email:
Phone:
Fax:


Type of strain

Would you like to submit your strain to a specific program within the The Jackson Laboratory Repository?

      

Genetically engineered targeted mutation

            Targeted gene  
            ES cell line
 
Genetically engineered transgene
            Transgene
            Promoter
            Founder Line Number
            Is there a common name
            for this strain?
 
Non-targeted, induced mutation (transgene insertion, gene trap, chemical, radiation)
            Affected gene  
            Method
 
Spontaneous mutation
            Strain Name  

If your strain fits the above categories, continue to questions 1-4, if not, please check one of the following 5 categories

Inbred

Recombinant Inbred

Recombinant Congenic

Consomic (Chromosome substitution)

CONTINUE TO QUESTIONS 5-8

Other (answer questions that apply)

1. Description of the mutation
Recessive     Dominant     Semi-Dominant
Molecular defect (if known)?


2. Mutant Phenotype
Are homozygous mice viable? Yes     No
  Comment
Are homozygous mice fertile? Yes     No
  Comment
Describe Phenotype, Major defects (if any)?


3. Strain genetic background
On what genetic background did strain originate? (include substrain if known)

On what genetic background is it maintained? (include substrain if known)

Is it inbred? Yes     No
If Yes, number of generations?

4a. Maintenance of the strain
What is your current breeding system?
   (examples: homozygous x homozygous; heterozygous x homozygous)

How good is reproduction?

Are there any special husbandry requirements?


4b. Mutant Identification
Do breeders require testing? Yes     No
What type of testing (Check all that apply)?
PCR
Southerns
Phenotype Identification
Other

 
IF YOU COMPLETED QUESTIONS 1-4, GO TO QUESTION 9
 

5. Strain Name


6. Strain Characteristics


7. Origin of Strain

Is this strain inbred? Yes     No
Number of generations?
For congenics, number of backcross generations?

8. Maintenance of the strain
What is your current breeding system?

How good is reproduction?

Are there any special husbandry requirements?


 
ALL SUBMISSIONS, PLEASE ANSWER THE FOLLOWING
 

9. Potential scientific value
What type of research is this strain useful for?

Does this strain model a human condition?

How good a model is it?


10. Are there similar strains in other laboratories?
Yes     No
How does yours differ from theirs?

Does anyone else maintain this strain?
Yes     No

Is this strain being distributed by or offered for distribution to any other institution, company or mouse repository?
Yes     No

If this is a genetically engineered strain, were any of the following technologies used at any point in its construction?
Cre-lox Technology
FLP Recombinase Technology
Tet-System Technology

11. Strain Demand
How many requests have you received for this strain in the last 6-12 months?

Size of requests?

Additional comments?


12. Would you be able to contribute to the cost of importation and cryopreservation?
Yes     No

13. Please list pertinent references or send a preprint if available. All manuscripts are treated confidentially.


14. Additional information you think it is important for the Committee to consider:


Please review the data in the form above before submitting. You will receive an email acknowledgement of your submission; please contact us if you do not receive the acknowledgement.